THE 5-SECOND TRICK FOR GENETIC METHYLATION TEST DUBLIN

Other unbiased epigenetic strategies contain methylated DNA immunoprecipitation (MeDIP). Sheared or enzyme-digested DNA fragments are matter to anti- 5′ -methylcytosine antibody binding for enrichment of methylated cytosine areas on the epigenome. Methylated fragments are purified and amplified for greater DNA yields (56, 67). A major limitation